業績/腎臓移植

1.   Harada H, Fukuzawa N, Abe T, Imamura R, Masaki N, Fujiyama N, Sato S, Hatakeyama S, Nishimura K, Kishikawa H, Iwami D, Hotta K, Miura M, Ide K, Nakamura M, Kosoku A, Uchida J, Murakami T, Tsuji T. Development and nationwide validation of kidney graft injury markers using urinary exosomes and microvesicles (complete English translation of the Japanese version). BMC Nephrol. 2023 Jun 6;24(1):158. doi: 10.1186/s12882-023-03189-z. PubMed PMID: 37280521; PubMed Central PMCID: PMC10242781.
2.   Taniguchi A, Kawamura M, Sakai S, Kimura-Ohba S, Tanaka Y, Fukae S, Tanaka R, Nakazawa S, Yamanaka K, Horio M, Takahara S, Nonomura N, Isaka Y, Imamura R, Kimura T. D-Asparagine is an Ideal Endogenous Molecule for Measuring the Glomerular Filtration Rate. Kidney Int Rep. 2023 Jun;8(6):1192-1200. doi: 10.1016/j.ekir.2023.03.009. eCollection 2023 Jun. PubMed PMID: 37284685; PubMed Central PMCID: PMC10239771.
3.   Imamura R, Takahara S, Yuzawa K. PREFACE. Transplant Proc. 2023 May;55(4):723. doi: 10.1016/j.transproceed.2023.04.019. Epub 2023 May 11. PubMed PMID: 37173261.
4.   Kado T, Tomimaru Y, Kobayashi S, Ito T, Imamura R, Sasaki K, Iwagami Y, Yamada D, Noda T, Takahashi H, Doki Y, Eguchi H. Clinical Impact of Ischemic Time of the Pancreas or Kidney Graft on Simultaneous Pancreas-Kidney Transplantation: A Single-Institution Study in Japan. Transplant Proc. 2023 May;55(4):969-973. doi: 10.1016/j.transproceed.2023.03.009. Epub 2023 Apr 7. PubMed PMID: 37032287.
5.   Matsui S, Namba-Hamano T, Maeda S, Nakamura J, Takahashi A, Kaimori JY, Fukae S, Tanaka R, Taniguchi A, Nakazawa S, Yamanaka K, Imamura R, Nonomura N, Isaka Y. A Case Report of a Kidney Transplant Recipient With Organizing Pneumonia After Graft Loss. Transplant Proc. 2023 May;55(4):1081-1083. doi: 10.1016/j.transproceed.2023.03.023. Epub 2023 Apr 15. PubMed PMID: 37069010.
6.   Taniguchi A, Miyashita K, Fukae S, Tanaka R, Nishida M, Kitayama T, Ouchi Y, Shimbo T, Nakazawa S, Yamanaka K, Imamura R, Tamai K, Nonomura N. Single-cell transcriptome analysis of a rat model of bilateral renal ischemia-reperfusion injury. Biochem Biophys Rep. 2023 Mar;33:101433. doi: 10.1016/j.bbrep.2023.101433. eCollection 2023 Mar. PubMed PMID: 36798850; PubMed Central PMCID: PMC9926196.
7.   Machiya S, Nakazawa S, Fukae S, Tanaka R, Taniguchi A, Yamanaka K, Takahara S, Namba-Hamano T, Imamura R, Nonomura N. Rapid deterioration of renal function following coronavirus disease 2019 in a renal transplant recipient. IJU Case Rep. 2022 Dec 16;6(2):120-3. doi: 10.1002/iju5.12566. [Epub ahead of print] PubMed PMID: 36718272; PubMed Central PMCID: PMC9878054.
8.   Kato T, Yoshida T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Yamanaka K, Abe T, Kishikawa H, Nonomura N, Imamura R. Incidence and mortality of post-transplant lymphoproliferative disorders after kidney transplantation: A real-world retrospective analysis in Japan. Int J Urol. 2022 Mar;29(3):206-211. doi: 10.1111/iju.14750. Epub 2021 Dec 12. PubMed PMID: 34897833.
9.   Miyagawa S, Kodama T, Matsuura R, Lo PC, Sakai R, Toyama C, Takama Y, Ihara Y, Kakuta Y, Yamanaka K, Matsunami K, Eguchi H, Maeda A, Okuyama H. A study of the mechanisms responsible for the action of new immunosuppressants and their effects on rat small intestinal transplantation. Transpl Immunol. 2022 Feb;70:101497. doi: 10.1016/j.trim.2021.101497. Epub 2021 Nov 14. Review. PubMed PMID: 34785307.
10.   Imamura R, Tanaka R, Taniguchi A, Nakazawa S, Kato T, Yamanaka K, Namba-Hamano T, Kakuta Y, Abe T, Tsutahara K, Takao T, Kishikawa H, Nonomura N. Everolimus Reduces Cancer Incidence and Improves Patient and Graft Survival Rates after Kidney Transplantation: A Multi-Center Study. J Clin Med. 2022 Jan 4;11(1). doi: 10.3390/jcm11010249. PubMed PMID: 35011990; PubMed Central PMCID: PMC8746009.
11.   Kawamura M, Hesaka A, Taniguchi A, Nakazawa S, Abe T, Hirata M, Sakate R, Horio M, Takahara S, Nonomura N, Isaka Y, Imamura R, Kimura T. Measurement of glomerular filtration rate using endogenous d-serine clearance in living kidney transplant donors and recipients. EClinicalMedicine. 2022 Jan;43:101223. doi: 10.1016/j.eclinm.2021.101223. eCollection 2022 Jan. PubMed PMID: 34934934; PubMed Central PMCID: PMC8654629.
12.   Iwata Y, Okushima H, Hesaka A, Kawamura M, Imamura R, Takahara S, Horio M, Tanaka Y, Ikeda T, Nakane M, Mita M, Hayashi T, Isaka Y, Kimura T. Identification of Diabetic Nephropathy in Patients Undergoing Kidney Biopsy through Blood and Urinary Profiles of d-Serine. Kidney360. 2021 Nov 25;2(11):1734-1742. doi: 10.34067/KID.0004282021. eCollection 2021 Nov 25. PubMed PMID: 35372995; PubMed Central PMCID: PMC8785851.
13.   Hesaka A, Tsukamoto Y, Nada S, Kawamura M, Ichimaru N, Sakai S, Nakane M, Mita M, Okuzaki D, Okada M, Isaka Y, Kimura T. d-Serine Mediates Cellular Proliferation for Kidney Remodeling. Kidney360. 2021 Oct 28;2(10):1611-1624. doi: 10.34067/KID.0000832021. eCollection 2021 Oct 28. PubMed PMID: 35372967; PubMed Central PMCID: PMC8785787.
14.   Obi Y, Ichimaru N, Sakaguchi Y, Iwadoh K, Ishii D, Sakai K, Iwami D, Harada H, Sumida K, Sekine A, Masutani K, Akutsu N, Inoue T, Nishihira M, Yoneda T, Ito S, Araki M, Kaimori JY, Yoshida K, Satoh S, Ubara Y, Isaka Y, Yoshida K, Tsubakihara Y, Takahara S, Hamano T. Correcting anemia and native vitamin D supplementation in kidney transplant recipients: a multicenter, 2 × 2 factorial, open-label, randomized clinical trial. Transpl Int. 2021 Jul;34(7):1212-1225. doi: 10.1111/tri.13885. Epub 2021 Jun 15. PubMed PMID: 33884674.
15.   Hirano SI, Aoki Y, Li XK, Ichimaru N, Takahara S, Takefuji Y. Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study. Med Gas Res. 2021 Jul-Sep;11(3):104-109. doi: 10.4103/2045-9912.314329. PubMed PMID: 33942780; PubMed Central PMCID: PMC8174412.
16.   Oshiro Y, Harada H, Hasegawa K, Akutsu N, Yoshizumi T, Kawagishi N, Nanmoku K, Ichimaru N, Okamura K, Ohira M, Itabashi Y, Fujiyama N, Ide K, Okajima H, Ogawa K, Takagi K, Eguchi H, Shinoda M, Nishida K, Shimazaki J, Shimoda M, Takahashi M, Okamoto H, Suzuki S. Loss of antibodies to hepatitis E virus in organ transplant patients with hepatitis E. Hepatol Res. 2021 May;51(5):538-547. doi: 10.1111/hepr.13637. Epub 2021 Apr 6. PubMed PMID: 33749100.
17.   Imamura R, Nakazawa S, Yamanaka K, Kakuta Y, Tsutahara K, Taniguchi A, Kawamura M, Kato T, Abe T, Uemura M, Takao T, Kishikawa H, Nonomura N. Cumulative cancer incidence and mortality after kidney transplantation in Japan: A long-term multicenter cohort study. Cancer Med. 2021 Apr;10(7):2205-2215. doi: 10.1002/cam4.3636. Epub 2020 Dec 13. PubMed PMID: 33314709; PubMed Central PMCID: PMC7982608.
18.   Zhao J, Que W, Du X, Fujino M, Ichimaru N, Ueta H, Tokuda N, Guo WZ, Zabrocki P, de Haard H, Nonomura N, Li XK. Monotherapy With Anti-CD70 Antibody Causes Long-Term Mouse Cardiac Allograft Acceptance With Induction of Tolerogenic Dendritic Cells. Front Immunol. 2020;11:555996. doi: 10.3389/fimmu.2020.555996. eCollection 2020. PubMed PMID: 33737923; PubMed Central PMCID: PMC7961176.
19.   Tanaka R, Kakuta Y, Tsutahara K, Nakagawa M, Ichimaru N, Sakaguchi K, Kato T, Imamura R, Nonomura N, Takao T. Successful recovery from coronavirus disease 2019 in a living kidney transplant recipient using low-dose methylprednisolone. IJU Case Rep. 2021 Jan;4(1):22-24. doi: 10.1002/iju5.12226. eCollection 2021 Jan. PubMed PMID: 33230502; PubMed Central PMCID: PMC7675346.
20.   Imamura R, Kawamura M, Taniguchi A, Kobayashi Y, Nakazawa S, Kato T, Abe T, Uemura M, Kobayashi H, Nonomura N. Efficacy of a Si-based agent against developing renal failure in a rat remnant kidney model. Biochem Biophys Res Commun. 2020 Dec 17;533(4):698-703. doi: 10.1016/j.bbrc.2020.10.067. Epub 2020 Oct 31. PubMed PMID: 33131768.
21.   Namba-Hamano T, Hamano T, Imamura R, Yamaguchi Y, Kyo M, Yonishi H, Takahashi A, Kawamura M, Nakazawa S, Kato T, Abe T, Kyakuno M, Takabatake Y, Nonomura N, Isaka Y. Recurrence of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits with a Striated Ultrastructure. Nephron. 2020;144 Suppl 1:43-48. doi: 10.1159/000512330. Epub 2020 Nov 23. PubMed PMID: 33227797.
22.   Matsumura S, Kato T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Abe T, Nonomura N, Imamura R. Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation. Ther Clin Risk Manag. 2020;16:947-952. doi: 10.2147/TCRM.S273388. eCollection 2020. PubMed PMID: 33116544; PubMed Central PMCID: PMC7549878.
23.   Imamura R, Matsuda Y, Tsutahara K, Nonomura N, Takahara S. Impact of Immunoglobulin M-Type Donor-Specific Human Leukocyte Antigen-Antibody Levels in Supernatants from Cultured Peripheral Blood Mononuclear Cells as Predictors of Antibody-Mediated Rejection. Pathogens. 2020 Sep 5;9(9). doi: 10.3390/pathogens9090733. PubMed PMID: 32899542; PubMed Central PMCID: PMC7559903.
24.   Doi Y, Hamano T, Ichimaru N, Tomida K, Obi Y, Fujii N, Yamaguchi S, Oka T, Sakaguchi Y, Matsui I, Kaimori JY, Abe T, Imamura R, Takahara S, Tsubakihara Y, Nonomura N, Isaka Y. Serum phosphate levels modify the impact of parathyroid hormone levels on renal outcomes in kidney transplant recipients. Sci Rep. 2020 Aug 13;10(1):13766. doi: 10.1038/s41598-020-70709-4. PubMed PMID: 32792668; PubMed Central PMCID: PMC7426845.
25.   Yamanaka K, Imamura R, Nakazawa S, Kato T, Kakuta Y, Abe T, Okumi M, Nonomura N. Therapeutic Effects and Functional Mechanism of Intravenous Immunoglobulin in Preclinical Rat Renal Transplant Model of Antibody-Mediated Rejection. Transplant Proc. 2020 Jul-Aug;52(6):1901-1905. doi: 10.1016/j.transproceed.2020.01.137. Epub 2020 May 1. PubMed PMID: 32362462.
26.   Takao M, Abe H, Sakai T, Hamada H, Takahara S, Sugano N. Transitional changes in the incidence of hip osteonecrosis among renal transplant recipients. J Orthop Sci. 2020 May;25(3):466-471. doi: 10.1016/j.jos.2019.06.009. Epub 2019 Jul 4. PubMed PMID: 31280930; PubMed Central PMCID: PMC7135379.
27.   Kobayashi Y, Imamura R, Koyama Y, Kondo M, Kobayashi H, Nonomura N, Shimada S. Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent. Sci Rep. 2020 Apr 3;10(1):5859. doi: 10.1038/s41598-020-62755-9. PubMed PMID: 32246095; PubMed Central PMCID: PMC7125117.
28.   Kawamura M, Imamura R, Kobayashi Y, Taniguchi A, Nakazawa S, Kato T, Namba-Hamano T, Abe T, Uemura M, Kobayashi H, Nonomura N. Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method. Front Med (Lausanne). 2020;7:95. doi: 10.3389/fmed.2020.00095. eCollection 2020. PubMed PMID: 32266279; PubMed Central PMCID: PMC7099649.
29.   Owada Y, Oshiro Y, Inagaki Y, Harada H, Fujiyama N, Kawagishi N, Yagisawa T, Usui J, Akutsu N, Itabashi Y, Saito K, Watarai Y, Ichimaru N, Imamura R, Kyakuno M, Ide K, Shibuya Y, Okabe Y, Ono M, Sasaki K, Shiose A, Yamagishi K, Ohnishi H, Nagashima S, Takahashi M, Yuzawa K, Okamoto H, Ohkohchi N. A Nationwide Survey of Hepatitis E Virus Infection and Chronic Hepatitis in Heart and Kidney Transplant Recipients in Japan. Transplantation. 2020 Feb;104(2):437-444. doi: 10.1097/TP.0000000000002801. PubMed PMID: 31205267; PubMed Central PMCID: PMC7004465.
30.   Takahashi K, Wakasugi M, Okudera H, Seto C, Furuki I, Hasegawa T, Takahara S. Importance of Continuing Education for Medical Staff to Improve the Confirmation Rate of Intent for Organ Donation. Transplant Proc. 2019 Dec;51(10):3213-3218. doi: 10.1016/j.transproceed.2019.08.043. PubMed PMID: 31810504.
31.   Zhao J, Yang XC, Fujino M, Ichimaru N, Que W, Li XK, Takahara S. Salvianolic acid B ameliorates liver injury in a murine aGvHD model by decreasing inflammatory responses via upregulation of HO-1. Transpl Immunol. 2019 Aug;55:101203. doi: 10.1016/j.trim.2019.03.002. Epub 2019 Mar 20. PubMed PMID: 30904623.
32.   Ichimaru N, Kawamura M, Nakazawa S, Kato T, Abe T, Kaimori JY, Imamura R, Moriyama T, Nonomura N. Adherence to Dietary Recommendations Measured by Smartphone-based Recipe Nutrition Calculator in Kidney Transplant Patients. Transplant Proc. 2019 Jun;51(5):1362-1364. doi: 10.1016/j.transproceed.2019.03.021. Epub 2019 May 7. PubMed PMID: 31076153.
33.   Nakazawa S, Imamura R, Kawamura M, Kato T, Abe T, Iwatani H, Yamanaka K, Uemura M, Kishikawa H, Nishimura K, Tajiri M, Wada Y, Nonomura N. Evaluation of IgA1 O-glycosylation in Henoch-Schönlein Purpura Nephritis Using Mass Spectrometry. Transplant Proc. 2019 Jun;51(5):1481-1487. doi: 10.1016/j.transproceed.2019.01.122. Epub 2019 May 10. PubMed PMID: 31084922.
34.   Kakuta Y, Imamura R, Okumi M, Horio M, Isaka Y, Ichimaru N, Takahara S, Nonomura N, Tanabe K. Assessment of renal function in living kidney donors before and after nephrectomy: A Japanese prospective, observational cohort study. Int J Urol. 2019 Apr;26(4):499-505. doi: 10.1111/iju.13923. Epub 2019 Feb 28. PubMed PMID: 30818421.
35.   Nakazawa S, Imamura R, Kawamura M, Kato T, Abe T, Namba T, Iwatani H, Yamanaka K, Uemura M, Kishikawa H, Nishimura K, Oka K, Tajiri M, Wada Y, Nonomura N. Difference in IgA1 O-glycosylation between IgA deposition donors and IgA nephropathy recipients. Biochem Biophys Res Commun. 2019 Jan 22;508(4):1106-1112. doi: 10.1016/j.bbrc.2018.12.014. Epub 2018 Dec 13. PubMed PMID: 30553446.
36.   Ikeda M, Shimizu K, Ogura H, Kurakawa T, Umemoto E, Motooka D, Nakamura S, Ichimaru N, Takeda K, Takahara S, Hirano SI, Shimazu T. Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis. Shock. 2018 Dec;50(6):640-647. doi: 10.1097/SHK.0000000000001098. PubMed PMID: 29293174.
37.   Li S, Fujino M, Ichimaru N, Kurokawa R, Hirano S, Mou L, Takahara S, Takahara T, Li XK. Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression. Sci Rep. 2018 Sep 19;8(1):14019. doi: 10.1038/s41598-018-32411-4. PubMed PMID: 30232347; PubMed Central PMCID: PMC6145907.
38.   Kakuta Y, Satoh S, Watarai Y, Aikawa A, Tanabe K, Harada H, Yagisawa T, Ishida H, Okumi M, Takahara S. Successful Desensitization of T cell Flow Cytometry Crossmatch Positive Renal Transplant Recipients Using Plasmapheresis and Super High-Dose Intravenous Immunoglobulin. Transplant Direct. 2018 Jan;4(1):e336. doi: 10.1097/TXD.0000000000000753. eCollection 2018 Jan. PubMed PMID: 29399625; PubMed Central PMCID: PMC5777667.
39.   Yamamoto S, Kaimori JY, Yoshimura T, Namba T, Imai A, Kobayashi K, Imamura R, Ichimaru N, Kato K, Nakaya A, Takahara S, Isaka Y. Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein. Nephrol Dial Transplant. 2017 Dec 1;32(12):2010-2017. doi: 10.1093/ndt/gfx083. PubMed PMID: 29156055.
40.   Li S, Takahara T, Fujino M, Fukuhara Y, Sugiyama T, Li XK, Takahara S. Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice. PLoS One. 2017;12(11):e0187810. doi: 10.1371/journal.pone.0187810. eCollection 2017. PubMed PMID: 29121675; PubMed Central PMCID: PMC5679630.
41.   Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG. NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology. Sci Rep. 2017 Aug 10;7(1):7733. doi: 10.1038/s41598-017-08284-4. PubMed PMID: 28798345; PubMed Central PMCID: PMC5552802.
42.   Takahashi K, Saito K, Takahara S, Fuchinoue S, Yagisawa T, Aikawa A, Watarai Y, Yoshimura N, Tanabe K, Morozumi K, Shimazu M. Results of a multicenter prospective clinical study in Japan for evaluating efficacy and safety of desensitization protocol based on rituximab in ABO-incompatible kidney transplantation. Clin Exp Nephrol. 2017 Aug;21(4):705-713. doi: 10.1007/s10157-016-1321-5. Epub 2016 Aug 17. PubMed PMID: 27534951.
43.   Kaimori JY, Isaka Y, Hatanaka M, Yamamoto S, Ichimaru N, Fujikawa A, Shibata H, Fujimori A, Miyoshi S, Yokawa T, Kuroda K, Moriyama T, Rakugi H, Takahara S. Visualization of kidney fibrosis in diabetic nephropathy by long diffusion tensor imaging MRI with spin-echo sequence. Sci Rep. 2017 Jul 18;7(1):5731. doi: 10.1038/s41598-017-06111-4. PubMed PMID: 28720778; PubMed Central PMCID: PMC5515876.
44.   Matsuda Y, Imamura R, Takahara S. Evaluation of Antigen-Specific IgM and IgG Production during an In Vitro Peripheral Blood Mononuclear Cell Culture Assay. Front Immunol. 2017;8:794. doi: 10.3389/fimmu.2017.00794. eCollection 2017. PubMed PMID: 28740496; PubMed Central PMCID: PMC5502262.
45.   Cai S, Hou J, Fujino M, Zhang Q, Ichimaru N, Takahara S, Araki R, Lu L, Chen JM, Zhuang J, Zhu P, Li XK. iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells. Stem Cell Reports. 2017 May 9;8(5):1174-1189. doi: 10.1016/j.stemcr.2017.03.020. Epub 2017 Apr 20. PubMed PMID: 28434942; PubMed Central PMCID: PMC5425686.
46.   Abe T, Yazawa K, Fujino M, Imamura R, Hatayama N, Kakuta Y, Tsutahara K, Okumi M, Ichimaru N, Kaimori JY, Isaka Y, Seki K, Takahara S, Li XK, Nonomura N. High-pressure carbon monoxide preserves rat kidney grafts from apoptosis and inflammation. Lab Invest. 2017 Apr;97(4):468-477. doi: 10.1038/labinvest.2016.157. Epub 2017 Feb 13. PubMed PMID: 28194034.
47.   Hagiwara K, Seto N, Shimizu Y, Takahara S. Involvement of Recipient Transplant Coordinators in Transplant Outpatient Clinics in Japan. Prog Transplant. 2017 Mar;27(1):48-52. doi: 10.1177/1526924816681008. Epub 2017 Jan 21. PubMed PMID: 27913799.
48.   Cai S, Ichimaru N, Takahara S. How Do Dendritic Cells Play the Role in Ischemia/Reperfusion Triggered Kidney Allograft Rejection. Curr Gene Ther. 2017;17(6):400-404. doi: 10.2174/1566523218666180214095956. Review. PubMed PMID: 29446738.
49.   Hayashi Y, Nagahara A, Kawashima A, Kakuta Y, Ujike T, Abe T, Fukuhara S, Fujita K, Uemura M, Kiuchi H, Imamura R, Miyagawa Y, Ichimaru N, Maeda T, Nonomura N. [A CASE OF SUCCESSFUL RECOVERY OF RENAL ALLOGRAFT FUNCTION FOLLOWING A DIAGNOSIS OF THROMBOTIC MICROANGIOPATHY CLINICALLY MADE IN THE IMMEDIATE POST-TRANSPLANT PERIOD]. Nihon Hinyokika Gakkai Zasshi. 2017;108(3):166-169. doi: 10.5980/jpnjurol.108.166. PubMed PMID: 30033982.
50.   Alachkar H, Mutonga M, Kato T, Kalluri S, Kakuta Y, Uemura M, Imamura R, Nonomura N, Vujjini V, Alasfar S, Rabb H, Nakamura Y, Alachkar N. Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection. BMC Nephrol. 2016 Nov 21;17(1):181. doi: 10.1186/s12882-016-0395-3. PubMed PMID: 27871261; PubMed Central PMCID: PMC5117555.
51.   Ishida H, Takahara S, Amada N, Tomikawa S, Chikaraishi T, Takahashi K, Uchida K, Akiyama T, Tanabe K, Toma H. A Prospective Randomized, Comparative Trial of High-Dose Mizoribine Versus Mycophenolate Mofetil in Combination With Tacrolimus and Basiliximab for Living Donor Renal Transplant: A Multicenter Trial. Exp Clin Transplant. 2016 Oct;14(5):518-525. PubMed PMID: 27733107.
52.   Ishida H, Takahara S, Amada N, Tomikawa S, Chikaraishi T, Takahashi K, Uchida K, Akiyama T, Tanabe K, Toma H. A Prospective Randomized, Comparative Trial of High-Dose Mizoribine Versus Mycophenolate Mofetil in Combination With Tacrolimus and Basiliximab for Living Donor Renal Transplant: A Multicenter Trial. Exp Clin Transplant. 2016 May 17;. doi: 10.6002/ect.2015.0326. [Epub ahead of print] PubMed PMID: 27210294.
53.   Cai S, Ichimaru N, Zhao M, Fujino M, Ito H, Ota U, Nakajima M, Tanaka T, Nonomura N, Li XK, Takahara S. Prolonged Mouse Cardiac Graft Cold Storage via Attenuating Ischemia-Reperfusion Injury Using a New Antioxidant-Based Preservation Solution. Transplantation. 2016 May;100(5):1032-40. doi: 10.1097/TP.0000000000001079. PubMed PMID: 26845308.
54.   Kaimori JY, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozaki N, Takahara S, Takao T, Ohkawa Y, Kimura H, Isaka Y. Histone H4 lysine 20 acetylation is associated with gene repression in human cells. Sci Rep. 2016 Apr 11;6:24318. doi: 10.1038/srep24318. PubMed PMID: 27064113; PubMed Central PMCID: PMC4827026.
55.   Yamanaka K, Kakuta Y, Miyagawa S, Nakazawa S, Kato T, Abe T, Imamura R, Okumi M, Maeda A, Okuyama H, Mizuno M, Nonomura N. Depression of Complement Regulatory Factors in Rat and Human Renal Grafts Is Associated with the Progress of Acute T-Cell Mediated Rejection. PLoS One. 2016;11(2):e0148881. doi: 10.1371/journal.pone.0148881. eCollection 2016. PubMed PMID: 26928779; PubMed Central PMCID: PMC4771804.
56.   Li S, Takahara T, Li XK, Fujino M, Sugiyama T, Tsukada K, Liu C, Kakuta Y, Nonomura N, Ito H, Takahashi K, Nakajima M, Tanaka T, Takahara S. 5-Aminolevulinic acid combined with ferrous iron ameliorate ischemia-reperfusion injury in the mouse fatty liver model. Biochem Biophys Res Commun. 2016 Feb 19;470(4):900-6. doi: 10.1016/j.bbrc.2016.01.136. Epub 2016 Jan 26. PubMed PMID: 26820535.
57.   Kato T, Kakuta Y, Abe T, Yamanaka K, Imamura R, Okumi M, Ichimaru N, Takahara S, Nonomura N. The benefits of cancer screening in kidney transplant recipients: a single-center experience. Cancer Med. 2016 Feb;5(2):153-8. doi: 10.1002/cam4.568. Epub 2015 Dec 21. PubMed PMID: 26686199; PubMed Central PMCID: PMC4735786.
58.   Hatanaka M, Kaimori JY, Yamamoto S, Matsui I, Hamano T, Takabatake Y, Ecelbarger CM, Takahara S, Isaka Y, Rakugi H. Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na+-H+ Exchanger-3 in Mice. PLoS One. 2016;11(1):e0147786. doi: 10.1371/journal.pone.0147786. eCollection 2016. PubMed PMID: 26807585; PubMed Central PMCID: PMC4725961.
59.   Maeda A, Eguchi H, Nakahata K, Lo PC, Yamanaka K, Kawamura T, Matsuura R, Sakai R, Asada M, Okuyama H, Miyagawa S. Monocytic MDSCs regulate macrophage-mediated xenogenic cytotoxicity. Transpl Immunol. 2015 Oct;33(2):140-5. doi: 10.1016/j.trim.2015.07.002. Epub 2015 Jul 21. PubMed PMID: 26209355.
60.   Kato T, Kakuta Y, Yamanaka K, Okumi M, Abe T, Imamura R, Ichimaru N, Takahara S, Nonomura N. Early diagnosis and treatment of breast cancer in Japanese kidney transplant recipients: a single center experience. Springerplus. 2015;4:196. doi: 10.1186/s40064-015-0946-2. eCollection 2015. PubMed PMID: 25992308; PubMed Central PMCID: PMC4431989.
61.   Kojima Y, Takahi Y, Ichimaru N, Okumi M, Takahara S, Nonomura N. Successful treatment of metastatic urothelial carcinoma arising in a transplanted renal allograft with paclitaxel, cisplatin, and gemcitabine combination therapy: a case report. BMC Res Notes. 2015 Feb 4;8:25. doi: 10.1186/s13104-015-0982-6. PubMed PMID: 25648269; PubMed Central PMCID: PMC4323029.
62.   Obi Y, Ichimaru N. [Clinical and epidemiological studies of kidney transplantation in Japan: a review of literature]. Nihon Jinzo Gakkai Shi. 2015;57(8):1303-10. Review. PubMed PMID: 26817156.
63.   Kato T, Okumi M, Tanemura M, Yazawa K, Kakuta Y, Yamanaka K, Tsutahara K, Doki Y, Mori M, Takahara S, Nonomura N. Adipose tissue-derived stem cells suppress acute cellular rejection by TSG-6 and CD44 interaction in rat kidney transplantation. Transplantation. 2014 Aug 15;98(3):277-84. doi: 10.1097/TP.0000000000000230. PubMed PMID: 24983309.
64.   Yamanaka K, Kyo M, Okumi M, Kato T, Kakuta Y, Ichimaru N, Takahara S, Nonomura N. The impact on graft survival of interstitial inflammation in borderline change of allograft kidneys. Nephrology (Carlton). 2014 Jun;19 Suppl 3:17-20. doi: 10.1111/nep.12242. PubMed PMID: 24842816.
65.   Obi Y, Hamano T, Ichimaru N, Tomida K, Matsui I, Fujii N, Okumi M, Kaimori JY, Yazawa K, Kokado Y, Nonomura N, Rakugi H, Takahara S, Isaka Y, Tsubakihara Y. Vitamin D deficiency predicts decline in kidney allograft function: a prospective cohort study. J Clin Endocrinol Metab. 2014 Feb;99(2):527-35. doi: 10.1210/jc.2013-2421. Epub 2013 Nov 27. PubMed PMID: 24285688.
66.   Tsuda H, Yamahara K, Otani K, Okumi M, Yazawa K, Kaimori JY, Taguchi A, Kangawa K, Ikeda T, Takahara S, Isaka Y. Transplantation of allogenic fetal membrane-derived mesenchymal stem cells protects against ischemia/reperfusion-induced acute kidney injury. Cell Transplant. 2014;23(7):889-99. doi: 10.3727/096368913X665594. Epub 2013 Apr 2. PubMed PMID: 23562186.
67.   Takahara S, Takahashi K, Akiyama T, Uchida K, Tanabe K, Amada N, Toma H. Randomized comparative trial of mizoribine versus mycophenolate mofetil in combination with tacrolimus for living donor renal transplantation. Clin Exp Nephrol. 2013 Dec;17(6):899-904. doi: 10.1007/s10157-013-0780-1. Epub 2013 Feb 21. PubMed PMID: 23430390.
68.   Takahashi K, Uchida K, Yoshimura N, Takahara S, Teraoka S, Teshima R, Cornu-Artis C, Kobayashi E. Efficacy and safety of concentration-controlled everolimus with reduced-dose cyclosporine in Japanese de novo renal transplant patients: 12-month results. Transplant Res. 2013 Jul 16;2(1):14. doi: 10.1186/2047-1440-2-14. PubMed PMID: 23866828; PubMed Central PMCID: PMC3718642.
69.   Danovitch GM, Chapman J, Capron AM, Levin A, Abbud-Filho M, Al Mousawi M, Bennett W, Budiani-Saberi D, Couser W, Dittmer I, Jha V, Lavee J, Martin D, Masri M, Naicker S, Takahara S, Tibell A, Shaheen F, Anantharaman V, Delmonico FL. Organ trafficking and transplant tourism: the role of global professional ethical standards-the 2008 Declaration of Istanbul. Transplantation. 2013 Jun 15;95(11):1306-12. doi: 10.1097/TP.0b013e318295ee7d. PubMed PMID: 23644753.
70.   Kaimori JY, Iwai S, Hatanaka M, Teratani T, Obi Y, Tsuda H, Isaka Y, Yokawa T, Kuroda K, Ichimaru N, Okumi M, Yazawa K, Rakugi H, Nonomura N, Takahara S, Kobayashi E. Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors. PLoS One. 2013;8(5):e63573. doi: 10.1371/journal.pone.0063573. Print 2013. PubMed PMID: 23667641; PubMed Central PMCID: PMC3647057.
71.   Kaimori JY, Ichimaru N, Isaka Y, Hashimoto F, Fu X, Hashimura Y, Kaito H, Iijima K, Kyo M, Namba T, Obi Y, Hatanaka M, Matsui I, Takabatake Y, Okumi M, Yazawa K, Nonomura N, Rakugi H, Takahara S. Renal transplantations from parents to siblings with autosomal recessive Alport syndrome caused by a rearrangement in an intronic antisense Alu element in the COL4A3 gene led to different outcomes. CEN Case Rep. 2013 May;2(1):98-101. doi: 10.1007/s13730-012-0049-7. Epub 2012 Dec 9. PubMed PMID: 28509228; PubMed Central PMCID: PMC5413733.
72.   Obi Y, Ichimaru N, Kato T, Kaimori JY, Okumi M, Yazawa K, Rakugi H, Nonomura N, Isaka Y, Takahara S. A single daily dose enhances the adherence to immunosuppressive treatment in kidney transplant recipients: a cross-sectional study. Clin Exp Nephrol. 2013 Apr;17(2):310-5. doi: 10.1007/s10157-012-0713-4. Epub 2012 Oct 23. PubMed PMID: 23089939.
73.   Horio M, Imai E, Yasuda Y, Watanabe T, Matsuo S. GFR estimation using standardized serum cystatin C in Japan. Am J Kidney Dis. 2013 Feb;61(2):197-203. doi: 10.1053/j.ajkd.2012.07.007. Epub 2012 Aug 11. PubMed PMID: 22892396.
74.   Nakazawa S, Imamura R, Yamamoto Y, Hayashi T, Tanigawa G, Fujita K, Hosomi M, Yamaguchi S. [Hyperuricemia and acute kidney injury following kidney transplantation : a case report]. Hinyokika Kiyo. 2013 Feb;59(2):103-6. PubMed PMID: 23552752.
75.   Nakazawa S, Imamura R, Hayashi T, Yamamoto Y, Tanigawa G, Fujita K, Hosomi M, Fushimi H, Yamaguchi S. [Urothelial carcinoma after renal transplantation : a case report]. Hinyokika Kiyo. 2013 Feb;59(2):117-20. PubMed PMID: 23552755.
76.   Tanabe K, Ishida H, Inui M, Okumi M, Shirakawa H, Shimizu T, Omoto K, Kondo T. ABO-incompatible kidney transplantation: long-term outcomes. Clin Transpl. 2013;:307-12. PubMed PMID: 25095522.
77.   Imamura R, Isaka Y, Sandoval RM, Ichimaru N, Abe T, Okumi M, Yazawa K, Kitamura H, Kaimori J, Nonomura N, Rakugi H, Molitoris BA, Takahara S. A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney. Clin Exp Nephrol. 2012 Dec;16(6):852-62. doi: 10.1007/s10157-012-0647-x. Epub 2012 Jun 8. PubMed PMID: 22678524; PubMed Central PMCID: PMC4108904.
78.   Tsuda H, Kawada N, Kaimori JY, Kitamura H, Moriyama T, Rakugi H, Takahara S, Isaka Y. Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress. Biochem Biophys Res Commun. 2012 Oct 19;427(2):266-72. doi: 10.1016/j.bbrc.2012.09.032. Epub 2012 Sep 17. PubMed PMID: 22995295.
79.   Obi Y, Ichimaru N, Hamano T, Tomida K, Matsui I, Fujii N, Okumi M, Kaimori JY, Yazawa K, Kokado Y, Tsubakihara Y, Nonomura N, Rakugi H, Takahara S, Isaka Y. Orally active vitamin d for potential chemoprevention of posttransplant malignancy. Cancer Prev Res (Phila). 2012 Oct;5(10):1229-35. doi: 10.1158/1940-6207.CAPR-12-0218. Epub 2012 Aug 27. PubMed PMID: 22926340.
80.   Tsutahara K, Okumi M, Kakuta Y, Abe T, Yazawa K, Miyagawa S, Matsunami K, Otsuka H, Kaimori J, Takahara S, Nonomura N. The blocking of CXCR3 and CCR5 suppresses the infiltration of T lymphocytes in rat renal ischemia reperfusion. Nephrol Dial Transplant. 2012 Oct;27(10):3799-806. doi: 10.1093/ndt/gfs360. Epub 2012 Aug 17. PubMed PMID: 22904101.
81.   Tomida K, Hamano T, Ichimaru N, Fujii N, Matsui I, Nonomura N, Tsubakihara Y, Rakugi H, Takahara S, Isaka Y. Dialysis vintage and parathyroid hormone level, not fibroblast growth factor-23, determines chronic-phase phosphate wasting after renal transplantation. Bone. 2012 Oct;51(4):729-36. doi: 10.1016/j.bone.2012.06.027. Epub 2012 Jul 14. PubMed PMID: 22796419.
82.   Abe T, Li XK, Yazawa K, Hatayama N, Xie L, Sato B, Kakuta Y, Tsutahara K, Okumi M, Tsuda H, Kaimori JY, Isaka Y, Natori M, Takahara S, Nonomura N. Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury. Transplantation. 2012 Jul 15;94(1):14-21. doi: 10.1097/TP.0b013e318255f8be. PubMed PMID: 22683850.
83.   Horio M, Yasuda Y, Kaimori J, Ichimaru N, Isaka Y, Takahara S, Nishi S, Uchida K, Takeda A, Hattori R, Kitada H, Tsuruya K, Imai E, Takahashi K, Watanabe T, Matsuo S. Performance of the Japanese GFR equation in potential kidney donors. Clin Exp Nephrol. 2012 Jun;16(3):415-20. doi: 10.1007/s10157-012-0586-6. Epub 2012 Jan 24. PubMed PMID: 22270186.
84.   Xie L, Ichimaru N, Morita M, Chen J, Zhu P, Wang J, Urbanellis P, Shalev I, Nagao S, Sugioka A, Zhong L, Nonomura N, Takahara S, Levy GA, Li XK. Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance. Liver Transpl. 2012 Apr;18(4):444-54. doi: 10.1002/lt.22480. PubMed PMID: 22162188.
85.   Abe T, Isaka Y, Imamura R, Kakuta Y, Okumi M, Yazawa K, Ichimaru N, Tsuda H, Nonomura N, Takahara S, Okuyama A. Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis. Cell Transplant. 2012;21(2-3):571-80. doi: 10.3727/096368911X605501. Epub 2012 Mar 8. PubMed PMID: 22410315.
86.   Xie L, Yamasaki T, Ichimaru N, Yui J, Kawamura K, Kumata K, Hatori A, Nonomura N, Zhang MR, Li XK, Takahara S. [(11)C]DAC-PET for noninvasively monitoring neuroinflammation and immunosuppressive therapy efficacy in rat experimental autoimmune encephalomyelitis model. J Neuroimmune Pharmacol. 2012 Mar;7(1):231-42. doi: 10.1007/s11481-011-9322-3. Epub 2011 Oct 29. PubMed PMID: 22038158.
87.   Kakuta Y, Okumi M, Miyagawa S, Tsutahara K, Abe T, Yazawa K, Matsunami K, Otsuka H, Takahara S, Nonomura N. Blocking of CCR5 and CXCR3 suppresses the infiltration of macrophages in acute renal allograft rejection. Transplantation. 2012 Jan 15;93(1):24-31. doi: 10.1097/TP.0b013e31823aa585. PubMed PMID: 22124337.
88.   Kitazawa Y, Li XK, Xie L, Zhu P, Kimura H, Takahara S. Bone marrow-derived conventional, but not cloned, mesenchymal stem cells suppress lymphocyte proliferation and prevent graft-versus-host disease in rats. Cell Transplant. 2012;21(2-3):581-90. doi: 10.3727/096368911X605510. PubMed PMID: 22793067.